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Health-related Quality of Life in Korean Patients with Rheumatoid Arthritis: Association with Pain, Disease Activity, Disability in Activities of Daily Living and Depression

Journal of Korean Academy of Nursing 2012³â 42±Ç 3È£ p.434 ~ 442
KMID : 0806120120420030434
¾öµ¿Ãá ( Uhm Dong-Choon ) - ´ëÀü´ëÇб³ ÀÀ±Þ±¸Á¶Çаú ±³¼ö

³²Àº¼÷ ( Nam Un-Suk ) - °­¿ø´ëÇб³ °£È£Çаú °Ç°­µ¹º½¿¬±¸¼Ò
ÀÌÈ£¿¬ ( Lee Ho Yeon ) - ¼­¿ïÀÇ·á¿ø ¼ö°£È£»ç
ÀÌÀººÀ ( Lee Eun-Bong ) - ¼­¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°ú
À±¿µÀÓ ( Yoon Young-Im ) - ¼­¿ï´ëÇб³º´¿ø ·ù¸¶Æ¼½º ±³À°½Ç °£È£»ç
ä°øÁÖ ( Chai Gong-Ju ) - ±¹¸³Ãáõº´¿ø Á¤½ÅÀü¹®°£È£»ç

Abstract

Purpose: The purpose of this predictive study was to identify factors affecting health related quality of life (HRQoL) in patients with rheumatoid arthritis (RA).

Methods: The participants in this study were 131 patients with RA who were recruited from the outpatient clinic of a university hospital in Seoul. Disease activity in rheumatoid arthritis was evaluated by calculating the Disease Activity Score 28. Disability in activities of daily living (ADL) was assessed with the Korean Health Assessment Questionnaire, and depression with The Center for Epidemiologic Studies Depression Scale. HRQoL was evaluated using The Short Form 36 Health Survey. Data were analyzed using descriptive statistics, correlation, and hierarchical multiple regression.

Results: Pain, disability in ADL, disease activity, and depression correlated negatively with physical and mental dimensions of HRQoL. But hierachical multiple regression analysis revealed that disability in ADL and depression were the only variables negatively influencing physical and mental QoL after adjustment for influences of sociodemographic variables.

Conclusion: Results of this study suggest that disability in ADL and depression, rather than disease activity and pain have profound effects on HRQoL in patients with RA. Further studies are needed to assess the predictive ability of disease activity and pain on HRQoL in this population.
KeyWords

Rheumatoid arthritis, Health related quality of life, Pain, Disability in ADL, Depression.
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